HOW MIGHT YOU DEFY IMAGINATION?
At Amgen, our shared mission – to serve patients – drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Amgen Research Copenhagen (ARC) is, through our DNA Encoded Library (DEL) technology, contributing significantly to Amgen’s many small molecule drug discovery projects from hit discovery all the way to drug candidate selection.
Come do your best work alongside other innovative, driven professionals in this thrilling and substantial role.
Fixed term (Senior) Scientist - Biology at Amgen Research Copenhagen, Denmark
WHAT YOU WILL DO
Let’s do this. Let’s change the world.
We are seeking a skilled Biologist who will be part of an exciting team bringing therapeutic projects from the early hit discovery stage through lead optimization in global collaboration with our colleagues in the US and other sites.
This is a temporary 18-month position for the coverage of parental leave.
As a member of the Amgen Research Copenhagen (ARC) Biosciences group, you will help us drive innovation within both traditional small molecule drug discovery and within discovery of novel proximity-inducing small molecule-based modalities including targeted protein degradation; one of the fastest growing new drug discovery modalities. Amgen has committed significantly to this new exciting field of drug discovery and the broad hit-finding platform at ARC is central for this effort. The position will involve development and/or implementation of novel cell-based methods for discovery and characterization of both traditional inhibitory and multi-specific small molecules and hit validation and mechanistic characterization using biochemical and cell-based methods. You will be working closely together with other biologists as well as medicinal chemists in the process of identifying and optimizing hits to reach project and company goals.
The employee will report to Senior Principal Scientist, Marie Morgan-Fisher.
Specifically, tasks will include:
Development, implementation, and execution of cell-based methods for discovery of novel small-molecule drug leads
Design and development of assays for mechanistic characterization of drug targets
Affinity and activity determination of hit molecules by biochemical and cell-based assays
Planning, execution, and analysis of experiments and screens according to project goals and timelines
Presentation of scientific results at team meetings, locally and across global sites
Multidisciplinary teamwork in a fast paced and diverse environment
WHAT WE EXPECT OF YOU
We are all different, yet we all use our outstanding contributions to serve patients. The qualified professional we seek is a driven individual with these qualifications:
BASIC QUALIFICATIONS
Ph.D. or equivalent in biochemistry, biomedicine, pharmacology, biotechnology, or a related discipline
Master’s degree or equivalent in biochemistry, biomedicine, pharmacology, biotechnology, or a related discipline and 2 years of laboratory experience from either academia or industry
Strong experience within cell biology
PREFERRED QUALIFICATIONS
Theoretical and hands-on experience with characterization of small molecule/drug target interactions using cell-based and biochemical assays
Understanding of structural biology and drug discovery
Experience within these fields is an advantage: Oncology, inflammation, metabolic diseases, the ubiquitin/proteasome system
Interest in handling, analyzing, and communicating complex data sets
Excellent laboratory skills and a keen interest in practical laboratory work
Excellent collaboration skills
Excellent English communication skills
Proactive personality with an urge for delivering high quality results
WHAT YOU CAN EXPECT FROM US
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. Amgen offers a Total Rewards Plan comprising health and welfare plans including:
Comprehensive employee benefits package, including generous company pension contribution, life and disability insurance and private healthcare insurance.
A discretionary annual bonus program
Competitive paid parental leave policy
Annual company-wide shutdown and additional vacation days
Flexible work model
We offer a highly exciting and stimulating environment in a world-class drug discovery organization. The position is based in our laboratories in Copenhagen.
If you’re seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you’ll find it at Amgen.
If you are passionate, creative, goal-oriented, open-minded, hardworking, and have a desire to do groundbreaking scientific research within a new field of drug discovery, please
APPLY NOW
FOR A CAREER THAT DEFIES IMAGINATION
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or disability status. Please note that it is required to have permit to live and work in Denmark for application.
All applications and contacts are confidential. We want your application as soon as possible since selection starts instantly.
For further information contact: Sr HR Coordinator Charlotte Rault (crault@amgen.com)