AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. The vision of AstraZeneca Respiratory & Immunology (R&I)iscenteredon delivering life-changing products that advance world health and help fight and cure disease. R&I is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. We are building new capabilities to support our growth in immunology and autoimmune diseases, and we have an exciting opportunity for an in vivo scientist looking to help bring new medicines to patients.
As a part of a growing in vivo Bioscience team within the R&I department, we areseekinga highly motivatedscientistwithhands-on in vivo skillsto join our collaborative team. This candidate would have experience in immunology or related discipline. This is a lab-based position. The role will initially be based in Waltham, MA within AstraZeneca’sstate-of-the-artlaboratories where you will follow the science to help drive innovation and advance medicine to help improve patient lives. InOctober2026 we will belocatedat the newstate of the artfacilities in Kendall Square Cambridge.
Main Duties and Responsibilities
In this role, you will be anin vivoexperimental scientist within Respiratory and Immunology Department focusing on developing therapeutics for the treatment of immune and autoimmune diseases such as SLE,fibrosisand arthritis using mouse models. You will generate preclinical and translational data in support of key portfolio programs and drive technical excellence in bioscience research.Strongexpertisein in vivo mouse modelsandhands-on in vivo skillsisrequiredand multiparameter flow cytometry, multiplex cytokine read-outs, qPCR is essential. The role will sometimes involve implementing protocols over timelines that extend outside of normal working patterns.
Accountabilities and responsibilities:
Practical In vivo experience and experimental skills in the use of animal modelsand tissue processingincluding mice handling,injections(IP,IV,SC,ID), PO dosing, blood collection. Tissue harvesting and processing for downstreamanalysis.
Immunology/autoimmunedisease knowledge, including target and mechanism knowledge (e.g. SLE, arthritis,Sjogren’s)
Why Join Us?
As part of AstraZeneca’s dynamic US biologics R&D community, you will play a critical role in shaping the future of AI-driven biologics discovery and engineering. Collaborating across cutting-edge computational and experimental teams, you’ll drive innovation that brings transformative medicines to patients around the world. You will be supported by a collaborative, inclusive, and empowering environment, with unparalleled opportunities for scientific impact and personal growth.
The annual base pay for this position ranges from $92,252.00 - $138,378.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Global job code
Date Posted
06-Apr-2026
Closing Date
29-Apr-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.