As we continue to develop our Biopharma business unit, we’re seeking an experienced and motivated Team Leader to oversee the cell culture / upstream process development activities in our growing Upstream Development Team. In this role you’ll manage a small team to lead our cell culture operations (revival, subculture, cryopreservation, day to day sampling, in-process analysis), optimising our mammalian process conditions through our ambr250 Bioreactors, small scale Bioreactors (and other process development equipment) to produce the strongest protein / antibody responses.
Working across the cell culture process / upstream process lifecycle, you’ll conduct daily monitoring activities from feeding and seeding into cell cultures, through inoculation and harvesting, to adjusting environmental factors and maintaining relevant temperature climates. To ensure the best results, you’ll undertake regular data analysis to check outputs and report results, such as cell density and viability characteristics, and troubleshoot technical activities to ensure all quality and safety requirements are met. To support the smooth running of the department, you’ll complete COSHH, risk assessment and peer review lab documentation, maintaining equipment-specific SOPs and experiment design runs (DoEs), producing data summary and progress reports, along with participating in safety inspections, stock checks and maintaining our ‘state of the art’ machines. In this exciting role, you’ll get the opportunity to learn and work collaboratively with the different workstream teams (in the UK and with our colleagues abroad from our established Biopharma unit at Intas Pharmaceuticals) and to grow with the team to support our ambitious growth plans.