This is what you will do:
The Associate Scientist III position is a technical positionconducting criticalanalytical testing and troubleshooting to support the development of Alexion’s biotherapeutic candidates. Under supervision, this position is also involved indevelopment and optimization of release and stability methods including process residuals, excipient analysis(e.g., PS80)and physiochemical chromatography (size exclusion, ion-exchange, reversed phase, hydrophobic interaction, etc.) for clinical and commercial biotherapeutics. Participation in method validation and transfer or troubleshooting of methods to internal and external laboratories may also be required. In addition, this position is expected to interact with scientific staff in other Research & Development groups as well as Manufacturing, Quality Assurance and Quality Control groups.
You will be responsible for:
Develop and optimize custom (U)HPLC chromatographic methods to evaluate key quality attributes for therapeutic proteins (SEC, RP-HPLC, Ion-Exchange, HIC, etc.)under the supervisionof LC team lead.
Participate in the operation, maintenance and troubleshooting of analytical instrumentation (e.g. UPLC, HPLC along with various detectors includingELSD, FLR, UV and QDA).
Follow and execute defined methods, SOPs. Under direct supervision, author SOPs, study plans, protocols, and method development reports.
The duties of this role are generally conducted in an lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours. Perform all job functions in compliance with cGXPs and maintainaccurate and legible laboratory records with a close attention to detail.
We would prefer for you to have:
A successful candidate will typically hold a BS. or M.S. degree in Chemistry, Biochemistry, or a biological science with 3+ years of relevant industry experience; or equivalent combination of education and experience.
Date Posted
19-Feb-2025
Closing Date
17-Apr-2025Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.